Title:A Review on Edible Vaccines and Biopharmaceutical Products from Plants
Volume: 24
Issue: 4
Author(s): Pankaj Kumar Paradia, Rameshwar Bhavale, Tejas Agnihotri and Aakanchha Jain*
Affiliation:
- 1Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research-Ahmedabad (NIPER-A),
(An Institute of National Importance, Government of India), Gujrat, India
Keywords:
Biopharmaceutical, edible vaccine, glycosylation, mass vaccination, plantibodies, transgenic plant.
Abstract: Plants have substantial potential for the development of various biopharmaceuticals.
Plants provide a cost-effective and direct source for the production of biopharmaceuticals such as
vaccines, antibodies, proteins, enzymes, and hormones. In most cases, purification is an important
and expensive step in the production of these substances. The problem can be resolved when it is
produced in plants and the whole plant can be consumed. Direct ingestion of plant materials may
help in overcoming the purification step. Being produced in seeds, fruits and tubers, it helps in
providing more immunization in developing countries at a cheaper rate. Moreover, it can be administered
more efficiently than any other dosage forms. This review focuses on various immunization
and therapeutic products that are produced in plants along with currently available formulations
in each category.