Title:Resveratrol Effects on Molecular Pathways and MicroRNAs in Gastrointestinal
Cancers
Volume: 30
Issue: 7
关键词:
白藜芦醇,胃肠道,癌症,microRNA,植物化学,肿瘤。
摘要: Gastrointestinal (GI) cancers are one of the most prevalent types of neoplasms
worldwide. The incidence of GI cancers is increasing rapidly. Despite all advances in the
management of GI cancers, treatment options for these disorders are still limited and
there are no effective therapeutic approaches. Hence, finding new treatment strategies
seems to be necessary to decrease mortality in patients with such cancers. The application
of natural products has found a prominent role in the management of some neoplastic
disorders. Resveratrol is a phytochemical found in various fruits and plants such as
red grapes and tea. Recently, the effects of resveratrol on the microRNAs in the management
of some neoplastic disorders have been investigated. This review is aimed to illustrate
the molecular pathways related to resveratrol and evaluate the impacts of resveratrol
on the different microRNAs in the milieu of the prevention and treatment of GI cancers.