Review Article

营养补充剂与铂类化疗之间相互作用的临床证据

卷 30, 期 19, 2023

发表于: 18 August, 2022

页: [2141 - 2164] 页: 24

弟呕挨: 10.2174/0929867329666220527120237

价格: $65

摘要

铂类药物,包括顺铂、奥沙利铂和卡铂,是化疗药物,代表了不同类型实体瘤的一线治疗,例如卵巢癌、头颈癌、睾丸癌和膀胱癌。它们的有益效果受到耐药性和严重毒性的发生的限制,主要涉及耳毒性、神经毒性和肾毒性。最近的研究强调补充具有抗氧化特性的草药产品、维生素和矿物质可以预防和防止副作用。特别是,与化疗相关的营养保健品的引入改善了患者的生活质量。然而,如果从一方面来说,补充和替代医学改善了化疗引起的毒性,那么从另一方面来说,重要的是要考虑到对药物代谢的可能干扰。本综述旨在考虑当前侧重于临床试验的文献,这些试验报告了营养保健品补充剂和基于铂的化学疗法之间的关联以预防毒性,并强调了有益和副作用。

关键词: 铂类药物,营养保健品,营养保健品补充剂,化疗,临床证据,毒性,相互作用。

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