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Cardiovascular & Hematological Agents in Medicinal Chemistry

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ISSN (Print): 1871-5257
ISSN (Online): 1875-6182

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Research Article

Effect of Magnesium Status on Microalbuminuria in Type 2 Diabetic Patients

Author(s): Maryam Rezaei, Reza Khazaei, Zabihullah Mohaqiq, Vajehallah Raeesi*, Tahereh Farkhondeh and Saeed Samarghandian*

Volume 21, Issue 1, 2023

Published on: 05 August, 2022

Page: [55 - 59] Pages: 5

DOI: 10.2174/1871525720666220425120457

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Abstract

Background: There are several controversies regarding the association between serum magnesium depletion and microalbuminuria in type 2 diabetic patients.

Objective: Therefore, this study aimed to assess serum magnesium concentrations in Type 2 diabetic patients with microalbuminuria and normoalbuminuria in Birjand, Iran, in 2019.

Methods: In this cross-sectional study, 25 type 2 diabetes patients with microalbuminuria were enrolled as the case group and 25 type 2 diabetes patients with normoalbuminuria as the control group. Both groups were matched for age, sex, hypertension, and dyslipidemia. Blood samples were obtained for serum magnesium measurement.

Results: Our findings showed no significant difference between serum magnesium concentration in the case and control groups (mean serum magnesium concentration for case group: 2.34 ± 0.35 mg/dl and control group: 2.27 ± 0.33 mg/dl). Pearson correlation coefficient analysis did not show any correlation between serum magnesium levels and urine albumin levels in patients with microalbuminuria versus patients with normoalbuminuria (r = 0.06, p = 0.67).

Conclusion: This study did not indicate a correlation between serum magnesium concentrations and microalbuminuria in Type 2 diabetic patients.

Keywords: Serum magnesium concentration, microalbuminuria, Type 2 diabetes, hypertension and dyslipidemia, blood samples, Pearson correlation coefficient analysis.

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