Title:Recent Patents on Plant-Derived Nanoparticles and their Potential
Application Towards Various Cancer Therapeutics
Volume: 18
Issue: 3
Author(s): S.B. Santhosh, Santny Shanmugarama, Nimma Ramesh*, A. Mohamed Sheik Tharik and Veera Vijaya Basamshetty*
Affiliation:
- Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Florida
A&M University, Tallahassee, USA
- Aptagen, Jacobus, Pennsylvania, USA
Keywords:
Herbal plants, nanoparticles, anticancer, treatments, patents, cytotoxicity.
Abstract:
Background: Nanotechnology plays a vital role in the field of medicine. Especially various
nanoparticles such as silver, gold, platinum are involved in the treatment of different types of
cancer. The effective nanoparticles were synthesized using techniques like chemical, physical, electrochemical
and biological methods. In order to overcome the limitations existing in the synthesis of
nanoparticles, researchers turned their attention toward the biological single step nanoparticle synthesis
method by using plant and plant products.
Objective: The objective of this study is to overcome the side effects encountered in the existing anti-
cancer agents like nonspecificity and fast excretion, and plant-derived nanoparticles that are ecofriendly,
cost-effective and biologically active could serve as a promising alternative.
Conclusion: From the thorough literature review and recent patents, it is understood that the plantderived
nanoparticles exhibited an excellent anti-proliferation anti-tumor activity towards different
types of cancers without affecting the normal cells. Especially, the traditional chemotherapeutic
drugs obtained from the plant source incorporated with the nanoparticles show remarkable results
against anti cancer studies. The present review focused on some of the existing herbal plant derived
nanoparticles, formulations and their potential application in cancer therapeutics.