Title:Circumstantial Insights into the Potential of Traditional Chinese Medicinal Plants as
a Therapeutic Approach in Rheumatoid Arthritis
Volume: 28
Issue: 26
Author(s): Twinkle Sharma, Parth Sharma, Parteek Chandel, Sukhbir Singh, Neelam Sharma, Tanveer Naved, Saurabh Bhatia, Ahmed Al-Harrasi, Simona Bungau and Tapan Behl*
Affiliation:
- Chitkara College of Pharmacy, Chitkara University, Punjab, India
Keywords:
Anti-inflammatory, anti-neovascularising, anti-nociceptive, Glycyrrhiza uralensis, Paeonia lactiflora, Sinomenium acutum, Tripterygium wilfordii.
Abstract: The advanced era has invited a plethora of chronic and autoimmune infirmities unmistakably dominated
by rheumatoid arthritis, occurring because of equivocal causes, including ecological factors, genetic variations,
etc. Unfortunately, it is winning pretty much in every stratum of the society in the undefined age group
of the population. Engineered drugs are accessible for the treatment; however, they do experience adverse effects
as the treatment requires a prolonged duration worsened by noncompliance. To overwhelm it, certain
pharmacological and molecular pathways are explored in the wake of Chinese herbs that prompted the prevention
of this deteriorating autoimmune disease. The alcoholic extracts and decoctions are procured from Chinese
herbs, such as Paeonia lactiflora, Glycyrrhiza uralensis, Tripterygium wilfordii, etc., which have been proved to
manifest constructive pharmacological actions. The activities that were exhibited by extracts are significantly innocuous,
non-toxic, and potent to fix the affliction in contrast with the chemosynthetic drugs. Therefore, these Chinese
herbs bring forth potent anti-inflammatory, immune-suppressing, anti-nociceptive, anti-neovascularizing, free
radical scavenging activities, and various other benefits to withstand several pathological events that usually
endure infirmity. It can be abridged that Chinese herbs possess assorted and selective therapeutic properties
with profound safety and viability to treat this rheumatic disorder. Thus, this review aims to shed light on naturally
originated treatment that is pertinent to providing invulnerable therapy exonerating from adverse effects
by restraining joint deformities, production of auto-antibodies, and inflammation.
