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Current Organic Synthesis

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ISSN (Print): 1570-1794
ISSN (Online): 1875-6271

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Review Article

Recent Advancements in the Design and Development of Near Infrared (NIR) Emitting Fluorescent Probes for Sensing and their Bio-Imaging Applications

Author(s): Natarajan Vijay, Kuppan Magesh, Renny Louis M and Sivan Velmathi*

Volume 20, Issue 1, 2023

Published on: 04 August, 2022

Page: [114 - 175] Pages: 62

DOI: 10.2174/1570179419666220308145901

Abstract

Fluorescent bio-imaging will be the future in the medical diagnostic for visualising inner cellular and tissues. Near-infrared (NIR) emitting fluorescent probes serve dynamically for targeted fluorescent imaging of live cells and tissues. NIR imaging is advantageous because of its merits like deep tissue penetration, minimum damage to the tissue, reduced auto fluorescence from the background, and improved resolution in imaging. The Development of the NIR emitting probe was well explored recently and growing drastically. In this review, we summarise recent achievements in NIR probes in between 2018-2021. The merits and future applications have also been discussed in this review.

Keywords: NIR probes, reactive oxygen, reactive sulphur species, hydrazine, bio imaging, fluorescent sensors.

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