Title:H19: A Vital Long Noncoding RNA in the Treatment of Diabetes and Diabetic
Complications
Volume: 28
Issue: 12
Author(s): Leiqi Zhu, Yuanyang Li, Fangqi Xia, Mengzhen Xue, Yaqi Wang, Dengke Jia, Yan Gao, Luoying Li, Yue Shi, Silong Chen, Guangfu Xu and Chengfu Yuan*
Affiliation:
- College of Medical Science, China Three Gorges University, Yichang 443002, China
- Third-Grade Pharmacological Laboratory
on Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges, Yichang, Hubei 443002, China
- Hubei Key Laboratory of Tumour Microenvironment and Immunotherapy, China Three Gorges
University, Yichang, China
Keywords:
H19, long noncoding RNA, miRNA, treatment, hyperglycemia, diabetes, diabetic complications.
Abstract:
Background: Increasing academic efforts have been made to explore the correlation of long noncoding
RNAs (lncRNAs) with human diseases, particularly metabolic diseases like diabetes mellitus. Taking lncRNA
H19 as an example, this review intends to reveal the functions and mechanism of lncRNA H19 in diabetes
mellitus and diabetic complications.
Methods: The research results associated with lncRNA H19 and diabetes mellitus are collected and summarized
on PubMed.
Conclusion: LncRNA H19 is a potential instructive marker for the treatment of diabetes mellitus and diabetic
complications.