Title:Cosmeceutical Aptitudes of Niacinamide: A Review
Volume: 16
Issue: 3
Author(s): Piyush Madaan, Priyanshi Sikka and Deepinder Singh Malik*
Affiliation:
- Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab,India
Keywords:
Co-crystals, dermatological disorders, nanoparticles, niacinamide, non-melanoma skin cancer, patents.
Abstract:
Background: The prevalence and scope of dermatological illness differ
from region to region. Based upon type and severity, the conditions may vary
from superficial to deep systemic skin infections. Niacinamide, an amide analog
of vitamin B3 which was conventionally utilized as a food supplement, is now explored
for the management of skin disorders. Being a powerhouse on its own, it
is not stored inside the body naturally and has to be acquired from external
sources.
Areas Covered: This review is an attempt to disclose the physiology, pharmacology,
and highlight the dermatological potentials of niacinamide, discussing its
pharmacological mechanisms, varied commercially available treatments, and novel
approaches, i.e., in research and patented formulations.
Results: Niacinamide has been verified in treating almost every skin disorder,
viz. aging, hyperpigmentation, acne, psoriasis, pruritus, dermatitis, fungal infections,
epidermal melasma, non-melanoma skin cancer, etc. It has been reported
to possess numerous properties, for instance, anti-inflammatory, antimicrobial,
antioxidant, antipruritic, and anticancer, which makes it an ideal ingredient for
varied dermal therapies. Long term use of niacinamide, regardless of the skin
type, paves the way for new skin cells, making skin healthier, brighter, and hydrated.
Conclusion: Niacinamide possesses a variety of positive characteristics in the
field of dermatology. Novel approaches are warranted over current treatments
which could bypass the above shortcomings and form an effective and stable system.
Hence, niacinamide has the potential to become an individual and a productive
component with wide future scope.
