Login Register Cart 0
Generic placeholder image

Current Pediatric Reviews

Editor-in-Chief

ISSN (Print): 1573-3963
ISSN (Online): 1875-6336

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Review Article

Quality of Life for Children with Allergic Skin Diseases

Author(s): Kam Lun Hon*, Samantha Chu and Alexander K.C. Leung

Volume 18, Issue 3, 2022

Published on: 25 February, 2022

Page: [191 - 196] Pages: 6

DOI: 10.2174/1573396317666210901124211

Price: $65

Open Access Journals Promotions 2
Abstract

Allergic skin diseases are highly prevalent among children. Patients with allergic skin diseases experience sociopsychological and quality-of-life (QoL) burdens in excess of those in the general population. Children and their caregivers are especially vulnerable to the burden of many of the common allergic skin diseases. In the past few decades, researchers have developed a number of disease-specific scores and indices for the measurement of QoL for childhood skin diseases. Most of the research in this area has focused on atopic eczema and urticaria and less so on allergic contact dermatitis. We provide an overview of QoL and its assessment for these dermatologic conditions.

Keywords: Life quality, atopic eczema, allergic contact dermatitis, urticaria, skin diseases, sociopsychological.

« Previous Next »
Graphical Abstract

[1]
Skin Allergy Symptoms Diagnosis, Treatment & Management. Skin Allergy. Available from: https://www.aaaai.org/conditions-and-treatments/allergies/skin-allergy
[2]
Leung AK, Hon KL, Robson WL. Atopic dermatitis. Adv Pediatr 2007; 54(1): 241-73.
[http://dx.doi.org/10.1016/j.yapd.2007.03.013] [PMID: 17918474]
[3]
Antia C, Baquerizo K, Korman A, Alikhan A, Bernstein JA. Urticaria: A comprehensive review: Treatment of chronic urticaria, special populations, and disease outcomes. J Am Acad Dermatol 2018; 79(4): 617-33.
[http://dx.doi.org/10.1016/j.jaad.2018.01.023] [PMID: 30241624]
[4]
Hon KL, Leung AKC, Ng WGG, Loo SK. Chronic urticaria: an overview of treatment and recent patents. Recent Pat Inflamm Allergy Drug Discov 2019; 13(1): 27-37.
[http://dx.doi.org/10.2174/1872213X13666190328164931] [PMID: 30924425]
[5]
Grob JJ, Gaudy-Marqueste C. Urticaria and quality of life. Clin Rev Allergy Immunol 2006; 30(1): 47-51.
[http://dx.doi.org/10.1385/CRIAI:30:1:047] [PMID: 16461995]
[6]
Brown MM, Chamlin SL, Smidt AC. Quality of life in pediatric dermatology. Dermatol Clin Rev Allergy Immunol 2013; 31(12): 211-.
[http://dx.doi.org/10.1016/j.det.2012.12.010]
[7]
Hon KL, Pong NH, Poon TC, et al. Quality of life and psychosocial issues are important outcome measures in eczema treatment. J Dermatolog Treat 2015; 26(1): 83-9.
[http://dx.doi.org/10.3109/09546634.2013.873762] [PMID: 24552300]
[8]
Lewis-Jones MS, Finlay AY. The Children’s Dermatology Life Quality Index (CDLQI): initial validation and practical use. Br J Dermatol 1995; 132(6): 942-9.
[http://dx.doi.org/10.1111/j.1365-2133.1995.tb16953.x] [PMID: 7662573]
[9]
Hon KL, Luk CK, Tsang YC, Pong NHH, Leung TF. Objective measurement of two clinical signs in childhood atopic eczema in research and therapeutics. J Dermatolog Treat 2017; 28(1): 47-9.
[http://dx.doi.org/10.1080/09546634.2016.1178376] [PMID: 27151659]
[10]
Holm EA, Wulf HC, Stegmann H, Jemec GBE. Life quality assessment among patients with atopic eczema. Br J Dermatol 2006; 154(4): 719-25.
[http://dx.doi.org/10.1111/j.1365-2133.2005.07050.x] [PMID: 16536816]
[11]
Ng WGG, Hon KL, Kung JSC, et al. Effect of pine-tar bath on disease severity in moderate-to-severe childhood eczema: An investigator-blinded, crossover, randomized clinical trial. J Dermatolog Treat 2020; 1-9.
[http://dx.doi.org/10.1080/09546634.2020.1732284] [PMID: 32066302]
[12]
Hon KL, Leung TF, Ng PC, et al. Efficacy and tolerability of a Chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study. Br J Dermatol 2007; 157(2): 357-63.
[http://dx.doi.org/10.1111/j.1365-2133.2007.07941.x] [PMID: 17501956]
[13]
Zalewska-Janowska A, Spiewak R, Kowalski ML. Cutaneous manifestation of drug allergy and hypersensitivity. Immunol Allergy Clin North Am 2017; 37(1): 165-81.
[14]
Yousefi P, Rasekhi S, Heshmati H. Quality of life in medical sciences. Intern J Med Res Health Sci 2016; 5(5): 43-6.
[15]
Schmitt J, Apfelbacher C, Spuls PI, et al. The Harmonizing Outcome Measures for Eczema (HOME) roadmap: a methodological framework to develop core sets of outcome measurements in dermatology. J Invest Dermatol 2015; 135(1): 24-30.
[http://dx.doi.org/10.1038/jid.2014.320] [PMID: 25186228]
[16]
Hon KL, Kam WY, Lam MC, Leung TF, Ng PC. CDLQI, SCORAD and NESS: are they correlated? Qual Life Res 2006; 15(10): 1551-8.
[http://dx.doi.org/10.1007/s11136-006-0019-7] [PMID: 16826438]
[17]
Smidt AC, Lai JS, Cella D, Patel S, Mancini AJ, Chamlin SL. Development and validation of Skindex-Teen, a quality-of-life instrument for adolescents with skin disease. Arch Dermatol 2010; 146(8): 865-9.
[http://dx.doi.org/10.1001/archdermatol.2010.161] [PMID: 20713817]
[18]
Leung TN, Hon KL. Eczema therapeutics in children: what do the clinical trials say? Hong Kong Med J 2015; 21(3): 251-60.
[http://dx.doi.org/10.12809/hkmj144474] [PMID: 25904389]
[19]
Leung DY, Bieber T. Atopic dermatitis. Lancet 2003; 361(9352): 151-60.
[http://dx.doi.org/10.1016/S0140-6736(03)12193-9] [PMID: 12531593]
[20]
Hon KL, Tsang S, Wong CY, et al. Atopy in children with eczema. Indian J Pediatr 2010; 77(5): 519-22.
[http://dx.doi.org/10.1007/s12098-010-0042-0] [PMID: 20422327]
[21]
Hon KLE, Liu M, Zee B. Airway disease and environmental aeroallergens in eczematics approaching adulthood. Pediatr Respirol Crit Care Med 2017; 1(4): 81.
[http://dx.doi.org/10.4103/prcm.prcm_18_17]
[22]
Lewis-Jones MS, Finlay AY, Dykes PJ. The infants’ dermatitis quality of life index. Br J Dermatol 2001; 144(1): 104-10.
[http://dx.doi.org/10.1046/j.1365-2133.2001.03960.x] [PMID: 11167690]
[23]
Kim DH, Li K, Seo SJ, et al. Quality of life and disease severity are correlated in patients with atopic dermatitis. J Korean Med Sci 2012; 27(11): 1327-32.
[http://dx.doi.org/10.3346/jkms.2012.27.11.1327] [PMID: 23166413]
[24]
Ražnatović Djurović M, Janković J, Tomić Spirić V, Janković S. Health-related quality of life in children with moderate to severe atopic dermatitis. Acta Dermatovenerol Croat 2015; 23(3): 178-84.
[PMID: 26476901]
[25]
Chamlin SL, Cella D, Frieden IJ, et al. Development of the childhood atopic dermatitis impact scale: Initial validation of a quality-of-life measure for young children with atopic dermatitis and their families. J Invest Dermatol 2005; 125(6): 1106-11.
[http://dx.doi.org/10.1111/j.0022-202X.2005.23911.x] [PMID: 16354179]
[26]
Deon KC, Santos DM, Bullinger M, Santos CB. Preliminary psycometric assessment of the Brazilian version of the DISABKIDS Atopic Dermatitis Module. Rev Saude Publica 2011; 45(6): 1072-8.
[http://dx.doi.org/10.1590/S0034-89102011005000067] [PMID: 21894429]
[27]
McKenna SP, Doward LC, Meads DM, Tennant A, Lawton G, Grueger J. Quality of life in infants and children with atopic dermatitis: Addressing issues of differential item functioning across countries in multinational clinical trials. Health Qual Life Outcomes 2007; 5: 45.
[http://dx.doi.org/10.1186/1477-7525-5-45] [PMID: 17662129]
[28]
Thomas KS, Koller K, Dean T, et al. A multicentre randomised controlled trial and economic evaluation of ion-exchange water softeners for the treatment of eczema in children: the Softened Water Eczema Trial (SWET). Health Technol Assess 2011; 15(8): v-vi, 1-156.
[http://dx.doi.org/10.3310/hta15080] [PMID: 21324289]
[29]
Campos ALB, Araújo FM, Santos MALD, Santos AASD, Pires CAA. Impact of atopic dermatitis on the quality of life of pediatric patients and their guardians. Rev Paul Pediatr 2017; 35(1): 5-10.
[http://dx.doi.org/10.1590/1984-0462/;2017;35;1;00006] [PMID: 28977306]
[30]
Ben Gashir MA, Seed PT, Hay RJ. Are quality of family life and disease severity related in childhood atopic dermatitis. J Europ Acad Dermatol Venereol 2002; 16(5): 455-65.
[31]
Chuh AA. Validation of a cantonese version of the children’s dermatology life quality index. Pediatr Dermatol 2003; 20(6): 479-81.
[http://dx.doi.org/10.1111/j.1525-1470.2003.20604.x] [PMID: 14651564]
[32]
Pariser DM, Simpson EL, Gadkari A, et al. Evaluating patient-perceived control of atopic dermatitis: design, validation, and scoring of the Atopic Dermatitis Control Tool (ADCT). Curr Med Res Opin 2020; 36(3): 367-76.
[http://dx.doi.org/10.1080/03007995.2019.1699516] [PMID: 31778083]
[33]
Howells LM, Chalmers JR, Gran S, et al. Development and initial testing of a new instrument to measure the experience of eczema control in adults and children: Recap of atopic eczema (RECAP). Br J Dermatol 2020; 183(3): 524-36.
[PMID: 31794074]
[34]
Shelley AJ, McDonald KA, McEvoy A, et al. Usability, satisfaction, and usefulness of an illustrated eczema action plan. J Cutan Med Surg 2018; 22(6): 577-82.
[http://dx.doi.org/10.1177/1203475418789028] [PMID: 30003800]
[35]
Powell K, Le Roux E, Banks JP, Ridd MJ. Developing a written action plan for children with eczema: A qualitative study. Br J Gen Pract 2018; 68(667): e81-9.
[http://dx.doi.org/10.3399/bjgp17X693617] [PMID: 29203680]
[36]
Brown J, Weitz NW, Liang A, Stockwell MS, Friedman S. Does an eczema action plan improve atopic dermatitis? A single-site randomized controlled trial. Clin Pediatr (Phila) 2018; 57(14): 1624-9.
[http://dx.doi.org/10.1177/0009922818795906] [PMID: 30141340]
[37]
Leung AKC, Hon KLE. Management of the child with food allergy. Food Allergies: Symptoms. Diagnosis, and Treatment, Nova Science Publishers 2011.
[38]
Hon KL, Leung TF. Neonatal urticaria due to American ginseng or not? Clin Exp Dermatol 2010; 35(1): 103-4.
[http://dx.doi.org/10.1111/j.1365-2230.2008.03079.x] [PMID: 20028409]
[39]
Hon KL, Li JTS, Leung AKC, Lee VWY. Current and emerging pharmacotherapy for chronic spontaneous Urticaria: A focus on non-biological therapeutics. Expert Opin Pharmacother 2021; 22(4): 497-509.
[http://dx.doi.org/10.1080/14656566.2020.1829593] [PMID: 32990110]
[40]
Itakura A, Tani Y, Kaneko N, Hide M. Impact of chronic urticaria on quality of life and work in japan: Results of a real-world study. J Dermatol 2018; 45(8): 963-70.
[http://dx.doi.org/10.1111/1346-8138.14502] [PMID: 29897137]
[41]
Kolkhir P, Altrichter S, Hawro T, Maurer M. C-reactive protein is linked to disease activity, impact, and response to treatment in patients with chronic spontaneous urticaria. Allergy 2018; 73(4): 940-8. http://doi.wiley.com/10.1111/all.13352
[http://dx.doi.org/10.1111/all.13352] [PMID: 29130488]
[42]
Beattie PE, Lewis-Jones MS. A comparative study of impairment of quality of life in children with skin disease and children with other chronic childhood diseases. Br J Dermatol 2006; 155(1): 145-51.
[http://dx.doi.org/10.1111/j.1365-2133.2006.07185.x] [PMID: 16792766]
[43]
Maurer M, Abuzakouk M, Bérard F, et al. The burden of chronic spontaneous urticaria is substantial: Real-world evidence from ASSURE-CSU. Allergy 2017; 72(12): 2005-16.
[http://dx.doi.org/10.1111/all.13209] [PMID: 28543019]
[44]
Kadyk DL, McCarter K, Achen F, Belsito DV. Quality of life in patients with allergic contact dermatitis. J Am Acad Dermatol 2003; 49(6): 1037-48.
[http://dx.doi.org/10.1016/S0190-9622(03)02112-1] [PMID: 14639382]
[45]
Chren MM. The skindex instruments to measure the effects of skin disease on quality of life. Dermatologic Clinics NIH Public Access 2012; 30: 231-6.
[46]
Kadyk DL, Hall S, Belsito DV. Quality of life of patients with allergic contact dermatitis: an exploratory analysis by gender, ethnicity, age, and occupation. Dermatitis 2004; 15(3): 117-24.
[http://dx.doi.org/10.2310/6620.2004.04007] [PMID: 15724345]
[47]
Botto N, Raffi J, Trivedi M, Ramirez F, Allen IE, Chren MM. Validating a quality-of-life instrument for allergic contact dermatitis. Dermatitis 2019; 30(5): 300-5.
[http://dx.doi.org/10.1097/DER.0000000000000515] [PMID: 31524758]
[48]
Raffi J, Elaine Allen I, Botto N. Validating responsiveness of a quality-of-life instrument for allergic contact dermatitis Dermat contact, atopic, Occup drug 2020; 31(3): 209-14.
[http://dx.doi.org/10.1097/DER.0000000000000542]

Rights & Permissions Print Cite
Article Metrics
63
1
Wayfinder Image
Open Access Journals Promotions
World Prematurity Day
© 2024 Bentham Science Publishers | Privacy Policy