Title:Stem Cells as a Potential Therapeutic Option for Treating Neurodegenerative Diseases
Volume: 17
Issue: 7
Author(s): L Aishwarya, Dharmarajan Arun and Suresh Kannan
Affiliation:
Keywords:
Stem cells, neurodegenerative diseases, conventional therapy, regeneration, stem cell treatment, preclinical and clinical trial.
Abstract: In future, neurodegenerative diseases will take over cancer's place and become the major
cause of death in the world, especially in developed countries. Advancements in the medical
field and its facilities have led to an increase in the old age population, and thus contributing to the
increase in number of people suffering from neurodegenerative diseases. Economically it is a great
burden to society and the affected family. No current treatment aims to replace, protect, and regenerate
lost neurons; instead, it alleviates the symptoms, extends the life span by a few months and
creates severe side effects. Moreover, people who are affected are physically dependent for performing
their basic activities, which makes their life miserable. There is an urgent need for therapy
that could be able to overcome the deficits of conventional therapy for neurodegenerative diseases.
Stem cells, the unspecialized cells with the properties of self-renewing and potency to differentiate
into various cells types, can become a potent therapeutic option for neurodegenerative diseases.
Stem cells have been widely used in clinical trials to evaluate their potential in curing different
types of ailments. In this review, we discuss the various types of stem cells and their potential use
in the treatment of neurodegenerative diseases-plural based on published preclinical and clinical
studies.