Title:Nanoantioxidant/Antioxidant Therapy in 2019-nCoV: A New Approach to Reactive Oxygen Species Mechanisms
Volume: 16
Issue: 4
Author(s): Ali Fathi Jouzdani, Rezvan Heidarimoghadam, Maryam Hazhirkamal and Akram Ranjbar*
Affiliation:
- Nutrition Health Research Center, Hamadan University of Medical Sciences, Hamadan,Iran
Keywords:
Antioxidants, COVID-19, nanoantioxidant, reactive oxygen species, mitochondria, organelles.
Abstract: The COVID-19 pandemic has caused serious concerns for people around the world. The
COVID-19 is associated with respiratory failure, generation of reactive oxygen species (ROS), and the
lack of antioxidants among patients. Specified ROS levels have an essential role as an adjuster of immunological
responses and virus cleaners, but excessive ROS will oxidize membrane lipids and cellular
proteins and quickly destroy virus-infected cells. It can also adversely damage normal cells in the
lungs and even the heart, resulting in multiple organ failures. Given the above, a highly potent antioxidant
therapy can be offered to reduce cardiac loss due to COVID-19. In modern medicine, nanoparticles
containing antioxidants can be used as a high-performance therapy in reducing oxidative stress in
the prevention and treatment of infectious diseases. This can provide a free and interactive tool to determine
whether antioxidants and nanoantioxidants can be administered for COVID-19. More research
and studies are needed to investigate and make definitive opinions about their medicinal uses.
