Title:A Review on Hematopoietic Stem Cell Treatment for Epilepsy
Volume: 20
Issue: 7
Author(s): Mohan Krishna Ghanta, Neha Merchant and Lakkakula V.K.S. Bhaskar*
Affiliation:
- Department of Zoology, Guru Ghasidas University, Bilaspur,India
Keywords:
Neuroprotection, neuronal regeneration, antiepileptic property, hematopoietic stem cell treatment, epilepsy,
seizure.
Abstract: Epilepsy responds to pharmacotherapy in its initial stages. The response of some forms
of epilepsy, like the refractory epilepsy, is extremely low. Surgical management of epilepsy is associated
with complications, which necessitates the search for novel and modern strategies for the
treatment of epilepsy. Neuroprotection and neuronal regeneration are the major targets that must be
accomplished by the new strategies. Hematopoietic Stem Cell (HSCs) therapy for epilepsy has
shown promising results in pre-clinical studies with marginal clinical effects. This review explores
the characteristics, mechanism of action, and clinical significance of HSCs therapy for the treatment
of epilepsy.
