Title:A Dig Deep to Scout the Pharmacological and Clinical Facet of Garlic
(Allium sativum)
Volume: 8
Issue: 1
Author(s): Mohd Masih Uzzaman Khan*, Habibullah Khalilullah, Eltayeb E.M. Eid, Faizul Azam, Masood Alam Khan, Arif Khan, Nasir Ali Siddiqui, Tarique Mahmood, Farogh Ahsan, Wasi Uzzaman Khan, Nitish Bhatia, Danish Mahmood and Md. Jamir Anwar
Affiliation:
- Department of Pharmaceutical Chemistry and Pharmacognosy, Unaizah College of Pharmacy, Qassim University,
Al-Qassim, Saudi Arabia
Keywords:
Garlic, Allium sativum, toxicity study, immunity, anti-microbial, hypertension.
Abstract: Garlic, Allium sativum L., is a culinary herb that has been employed medicinally since
ancient times. Garlic has been regarded as the oldest of all cultivated plants. Various experimental
as well as human studies have demonstrated that garlic is used in preventing the initiation and evolution
of several ailments such as hypertension, atherosclerosis, diabetes mellitus, cancer, microbial
infections, arthritis, thrombosis, and Alzheimer’s disease. It can also act as an anti-oxidant.
The preclinical toxicity study gives an impression that garlic is safe, although allergic reactions
may occur. Recently, there has been systematic research regarding garlic, and positive results have
been attained in healing many diseases. For centuries many countries of different civilizations and
continents protected their populations and healed themselves using garlic. Therefore, there is an
augmented necessity of investigation on the history of garlic for the sake of strengthening the ability
of physicians and pharmacists to deal with the challenges arising in the provision of specialized
facilities to serve mankind. The present review provides morphological, pharmacological, and toxicological
insight regarding garlic. Further studies are required to explicate the therapeutic mode of
action of garlic along with its potency, effectiveness, and clinical wellbeing in the management of
different ailments.
