Generic placeholder image

Current Respiratory Medicine Reviews

Editor-in-Chief

ISSN (Print): 1573-398X
ISSN (Online): 1875-6387

Research Article

The Role of LVOT-VTI Measurement in the Evaluation of Systolic Heart Function in Pulmonary ICU Patients

Author(s): Meltem Çimen, Selin Eyüboğlu, Uğur Özdemir*, Burhan Sami Kalın, Tuba Güney and Gül Gürsel

Volume 16, Issue 4, 2020

Page: [234 - 239] Pages: 6

DOI: 10.2174/1573398X16999201222123512

Price: $65

Open Access Journals Promotions 2
Abstract

Introduction: The detection of cardiac systolic dysfunction is very important for well management of pulmonary critical care patients (PCCPs). However, there is a poor correlation between echocardiographic cardiac systolic function (CSF) parameters and it is not easy to obtain these parameters in PCCPs. Therefore, this cross-sectional observational study was planned for the detection of a more easily obtainable echocardiographic CSF parameter that is well correlated with other CSF parameters in PCCPs.

Materials and Methods: Total 88 PCCPs were included. Demographic and clinical information and laboratory tests of all patients were recorded. The CSF parameters of the heart were obtained by transthoracic echocardiography with appropriate technique. LVOT-VTI (Left ventricular outflow tract velocity time integral), CO (cardiac output), EPSS (e point septal separation), Left ventricular EF (ejection fraction) and TAPSE (Tricuspid Annular Plane Systolic Excursion) as an indicator of CSF were tried to obtain from all patients. We also calculated sensitivity, specificity, positive and negative predictive values of LVOT-VTI<20 parameters to diagnose heart failure.

Results: The mean age of the patients was 73±12, 40% were female, 38% were intubated and 52% had COPD. LVOT-VTI, EF, CO, EPSS parameters were obtained in 54(61%), 24(27%), 48(54%), 48(54%) patients, respectively. Decreased LVOT-VTI (<20 cm) was well correlated with decreased EF (<45%) (p=0.001, r=0.77), decreased CO (<5 L/dk) (p=0.03, r=0.64) and decreased TAPSE (<17 mm) (p=0.001, r=0.71). Also, there was good agreement between the EF and LVOTVTI measurements (Kappa:0.78, p:0.001). Sensitivity, specificity, positive and negative predictive values of LVOT-VTI<20 for heart failure were 58, 78, 84, 49, repectively.

Conclusion: LVOT-VTI is a more easily obtainable and well correlated parameter, which can be used as an indicator of CSF in PCCPs.

Clinical Significances: The authors believe that LVOT-VTI measurement has good correlation with other echocardiographic systolic function parameters, and its easy measurement in intensive care patients makes it a very useful test for cardiac systolic function evaluation.

Keywords: COPD, LVOT-VTI, systolic dysfunction, transthoracic echocardiography, ICU, respiratory failure.

[1]
Bhatt SP, Dransfield MT. Chronic obstructive pulmonary disease and cardiovascular disease. Transl Res 2013; 162(4): 237-51.
[http://dx.doi.org/10.1016/j.trsl.2013.05.001] [PMID: 23727296]
[2]
Vogelmeier CF, Criner GJ, Martinez FJ, et al. Global strategy for the diagnosis, management and prevention of chronic obstructive lung disease 2017 Report: GOLD Executive Summary. Respirology 2017; 22(3): 575-601.
[http://dx.doi.org/10.1111/resp.13012] [PMID: 28150362]
[3]
Dittoe N, Stultz D, Schwartz BP, Hahn HS. Quantitative left ventricular systolic function: from chamber to myocardium. Crit Care Med 2007; 35(8), (Suppl.): S330-9.
[http://dx.doi.org/10.1097/01.CCM.0000270245.70103.7E] [PMID: 17667457]
[4]
Weekes AJ, Reddy A, Lewis MR, Norton HJ. E-point septal separation compared to fractional shortening measurements of systolic function in emergency department patients: prospective randomized study. J Ultrasound Med 2012; 31(12): 1891-7.
[http://dx.doi.org/10.7863/jum.2012.31.12.1891] [PMID: 23197541]
[5]
Schmid E, Hilberath JN, Blumenstock G, et al. Tricuspid annular plane systolic excursion (TAPSE) predicts poor outcome in patients undergoing acute pulmonary embolectomy. Heart Lung Vessel 2015; 7(2): 151-8.
[PMID: 26157741]
[6]
Lang RM, Badano LP, Mor-Avi V, et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging 2015; 16(3): 233-70.
[http://dx.doi.org/10.1093/ehjci/jev014] [PMID: 25712077]
[7]
Klaeboe LG, Edvardsen T. Echocardiographic assessment of left ventricular systolic function. J Echocardiogr 2019; 17(1): 10-6.
[http://dx.doi.org/10.1007/s12574-018-405-5] [PMID: 30390189]
[8]
Wang TJ, Evans JC, Benjamin EJ, Levy D, LeRoy EC, Vasan RS. Natural history of asymptomatic left ventricular systolic dysfunction in the community. Circulation 2003; 108(8): 977-82.
[http://dx.doi.org/10.1161/01.CIR.0000085166.44904.79] [PMID: 12912813]
[9]
Sevilla Berrios RA, O’Horo JC, Velagapudi V, Pulido JN. Correlation of left ventricular systolic dysfunction determined by low ejection fraction and 30-day mortality in patients with severe sepsis and septic shock: a systematic review and meta-analysis. J Crit Care 2014; 29(4): 495-9.
[http://dx.doi.org/10.1016/j.jcrc.2014.03.007] [PMID: 24746109]
[10]
Safford RE, Blackshear JL, Kapples EJ. Clinical utility of transesophageal echocardiography. South Med J 1991; 84(5): 611-8.
[PMID: 2035082]
[11]
Prada G, Vieillard-Baron A, Martin AK, Hernandez A, Mookadam F, Ramakrishna H, et al. Echocardiographic Applications of M-Mode Ultrasonography in Anesthesiology and Critical Care. J Cardiothorac Vasc Anesth 2018.
[12]
Stevens SM, Farzaneh-Far R, Na B, Whooley MA, Schiller NB. Development of an echocardiographic risk-stratification index to predict heart failure in patients with stable coronary artery disease: the Heart and Soul study. JACC Cardiovasc Imaging 2009; 2(1): 11-20.
[http://dx.doi.org/10.1016/j.jcmg.2008.08.004] [PMID: 19356527]
[13]
Picano E, Pellikka PA. Ultrasound of extravascular lung water: a new standard for pulmonary congestion. Eur Heart J 2016; 37(27): 2097-104.
[http://dx.doi.org/10.1093/eurheartj/ehw164]
[14]
Sabbah HN, Khaja F, Brymer JF, et al. Noninvasive evaluation of left ventricular performance based on peak aortic blood acceleration measured with a continuous-wave Doppler velocity meter. Circulation 1986; 74(2): 323-9.
[http://dx.doi.org/10.1161/01.CIR.74.2.323] [PMID: 3731423]
[15]
Goldman JH, Schiller NB, Lim DC, Redberg RF, Foster E. Usefulness of stroke distance by echocardiography as a surrogate marker of cardiac output that is independent of gender and size in a normal population. Am J Cardiol 2001; 87(4): 499-502, A8.
[http://dx.doi.org/10.1016/S0002-9149(00)01417-X] [PMID: 11179548]
[16]
Bergenzaun L, Gudmundsson P, Öhlin H, et al. Assessing left ventricular systolic function in shock: evaluation of echocardiographic parameters in intensive care. Crit Care 2011; 15(4): R200.
[http://dx.doi.org/10.1186/cc10368] [PMID: 21846331]
[17]
Navaratnam M, Punn R, Ramamoorthy C, Tacy TA. LVOT-VTI is a Useful Indicator of Low Ventricular Function in Young Patients. Pediatr Cardiol 2017; 38(6): 1148-54.
[http://dx.doi.org/10.1007/s00246-017-1630-9] [PMID: 28534242]
[18]
Feissel M, Michard F, Mangin I, Ruyer O, Faller JP, Teboul JL. Respiratory changes in aortic blood velocity as an indicator of fluid responsiveness in ventilated patients with septic shock. Chest 2001; 119(3): 867-73.
[http://dx.doi.org/10.1378/chest.119.3.867] [PMID: 11243970]
[19]
Tan C, Rubenson D, Srivastava A, et al. Left ventricular outflow tract velocity time integral outperforms ejection fraction and Doppler-derived cardiac output for predicting outcomes in a select advanced heart failure cohort. Cardiovasc Ultrasound 2017; 15(1): 18.
[http://dx.doi.org/10.1186/s12947-017-0109-4] [PMID: 28673293]
[20]
Maizel J, Salhi A, Tribouilloy C, Massy ZA, Choukroun G, Slama M. The subxiphoid view cannot replace the apical view for transthoracic echocardiographic assessment of hemodynamic status. Crit Care 2013; 17(5): R186.
[http://dx.doi.org/10.1186/cc12869] [PMID: 24004960]
[21]
Jensen MB, Sloth E, Larsen KM, Schmidt MB. Transthoracic echocardiography for cardiopulmonary monitoring in intensive care. Eur J Anaesthesiol 2004; 21(9): 700-7.
[http://dx.doi.org/10.1097/00003643-200409000-00006] [PMID: 15595582]
[22]
Matamis D, Tsagourias M, Papathanasiou A, et al. Targeting occult heart failure in intensive care unit patients with acute chronic obstructive pulmonary disease exacerbation: effect on outcome and quality of life. J Crit Care 2014; 29(2): 315.e7-315.e14.
[http://dx.doi.org/10.1016/j.jcrc.2013.11.011] [PMID: 24369757]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy