Title:Recent Advances in Molecular Hydrogen Research Reducing Exercise-Induced Oxidative Stress and Inflammation
Volume: 27
Issue: 5
Author(s): Jonatas E. Nogueira and Luiz G.S. Branco*
Affiliation:
- Department of Basic and Oral Biology, Dental School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP,Brazil
Keywords:
Physical exercise, cytokines, ROS, muscle, inflammatory response, plasma, rats, human.
Abstract: Physical exercise-induced oxidative stress and inflammation may be beneficial when exercise is a
regular activity, but it is rather harmful when exercise is exhaustive and performed by unaccustomed organisms.
Molecular hydrogen (H2) has recently appeared as a potent antioxidant and anti-inflammatory molecule in numerous
pathological conditions. However, its role is relatively unknown under physiological conditions such as
physical exercise. Therefore, this review summarizes the current knowledge of the H2, reducing oxidative stress
and inflammation in physical exercise, reporting data from both animal and human studies.