Title:Traditional Chinese Medicine Network Pharmacology in Cardiovascular Precision Medicine
Volume: 27
Issue: 26
Author(s): Li Gao*, Min Cao, Jia-qi Li, Xue-mei Qin and Jiansong Fang*
Affiliation:
- Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006,China
- Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405,China
Keywords:
Cardiovascular disease, omics, traditional Chinese medicine, precision medicine, network pharmacology, transcriptome, metabolomics.
Abstract: Cardiovascular disease is a major disease affecting human health, and its pathogenesis is caused by
many factors. Through the use of "omics" technology, precision medicine is playing an increasingly important
role in the prevention and treatment of cardiovascular diseases. Dialectical treatment with traditional Chinese
medicine (TCM will result in personalized treatment, which is consistent with precision medicine to a certain
extent. However, due to the multitarget, multipath, and multistep characteristics of TCM, its mechanism of action
is not easy to elucidate. Network pharmacology can be used to predict the mechanism, toxicity and metabolic
characteristics of TCM. This review summarizes commonly used bioinformatics resources for cardiovascular
diseases and TCM, as well as the opportunities and challenges of TCM in cardiovascular precision medicine,
with special emphasis on network pharmacology methods.
