Title:Cardiac Biomarkers in Stroke, Alzheimer’s Disease, and Other Dementia. Are They of Use? A Brief Overview of Data from Recent Investigations
Volume: 20
Issue: 8
Author(s): Shahzad Khan*Mohammad Amjad Kamal
Affiliation:
- Department of Pathophysiology, Wuhan University School of Medicine, Hubei, Wuhan 430071,China
Keywords:
Cardiac biomarker, BNP, troponin, Alzheimer's disease, stroke, pneumonia.
Abstract: Conventionally, cardiac biomarkers are recognized as an essential tool to investigate the
presence or progression of various cardiovascular diseases. However, in recent years, data from several
clinical trials have successfully sorted out the utility of cardiac biomarkers in diseases that are
not primarily regarded as “cardiac diseases,” especially neurological diseases. Results of freshly
published trials have endorsed the use of cardiac biomarkers in various forms of stroke and dementia,
including Alzheimer’s disease. Alzheimer’s disease is also one of the other CNS conditions
where measuring cardiac biomarkers have been found to be useful. Cardiac biomarkers can be helpful
in two ways. Firstly, to assess the secondary involvement of the heart during the progression of
the primary disease. Secondly, they can be useful in the diagnosis and prognosis of the primary condition
itself. In this short review, we have collected encouraging results from recent studies that
show the importance of the most widely recognized cardiac biomarkers in two of the most prominent
neurological diseases of the current world, i.e., stroke and dementia.
