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Current Topics in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1568-0266
ISSN (Online): 1873-4294

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Editorial

Most Promising Compounds for Treating COVID-19 and Recent Trends in Antimicrobial & Antifungal Agents

Author(s): Anuraj Nayarisseri*

Volume 20, Issue 24, 2020

Page: [2119 - 2125] Pages: 7

DOI: 10.2174/156802662023201001094634

Abstract

Multidrug resistance in microbes poses a major health crisis and demands for the discovery of novel antimicrobial agents. The recent pandemic of SARS-CoV-2 has raised a public health emergency in almost all the countries of the world. Unlike viruses, a bacterium plays a significant role in various environmental issues such as bioremediation. Furthermore, biosurfactants produced by various bacterial species have an edge over traditionally produced chemical surfactants for its biodegradability, low toxicity and better interfacial activity with various applications in agriculture and industry. This special issue focuses on the global perspective of drug discovery for various antimicrobial, antiviral, and antifungal agents for infectious diseases. The issue also emphasizes the ongoing developments and the role of microbes in environmental remediation. We wish the articles published in this issue will enhance the current understanding in microbiology among the readers, and serve as the "seed of an idea" for drug development for ongoing COVID-19 pandemic.

Keywords: Antiviral agents, Antimicrobial agents, Antifungal agents, COVID-19, COVID-19 inhibitors, Remdesivir, nCorvEMBS.

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Khandelwal, R.; Chauhan, A.P.S.; Bilawat, S.; Gandhe, A.; Hussain, T.; Hood, E.A.; Nayarisseri, A.; Singh, S.K. Structure-based virtual screening for the identification of high affinity small molecule towards STAT3 for the clinical treatment of Osteosarcoma. Curr. Top. Med. Chem., 2018, 18(29), 2511-2526.
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Monteiro, A.F.M.; Viana, J.O.; Nayarisseri, A.; Zondegoumba, E.N.; Mendonça, Junior, F.J.B.; Scotti, M.T.; Scotti, L. Computational studies applied to flavonoids against alzheimer’s and parkinson’s diseases. Oxid. Med. Cell. Longev., 2018, 2018, 7912765.
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Patidar, K.; Panwar, U.; Vuree, S.; Sweta, J.; Sandhu, M.K.; Nayarisseri, A.; Singh, S.K. An in silico approach to identify high affinity small molecule targeting m-tor inhibitors for the clinical treatment of breast cancer. Asian Pac. J. Cancer Prev., 2019, 20(4), 1229-1241.
[http://dx.doi.org/10.31557/APJCP.2019.20.4.1229 ] [PMID: 31030499]
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Sharda, S.; Khandelwal, R.; Adhikary, R.; Sharma, D.; Majhi, M.; Hussain, T. A computer-aided drug designing for pharmacological inhibition of ALK inhibitors induces apoptosis and differentiation in Non-small cell lung cancer. Curr. Top. Med. Chem., 2019, 19(13), 1129-1144.
[http://dx.doi.org/10.2174/1568026619666190521084941 ] [PMID: 31109278]

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