Title:Challenges in the Management of Pregnancy and Lactation Associated Osteoporosis: Literature Review and Retrospective Study
Volume: 16
Issue: 6
Author(s): Bo Yang, Lingbo Kong*Dingjun Hao*
Affiliation:
- Department of Spine, Honghui-Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an,China
- Department of Spine, Honghui-Hospital, School of Medicine, Xi’an Jiaotong University, Xi’an,China
Keywords:
Pregnancy, lactation associated osteoporosis, vertebral fracture, bisphosphonates, BMD, therapy.
Abstract: Pregnancy and lactation-associated osteoporosis (PLO) is a rare and special form of osteoporosis,
which is poorly known with regard to its etiology, pathophysiology and therapy. However,
PLO can cause vertebral compression fractures (VCFs) and height loss, which could cause
further kyphosis of the spine. Therefore, PLO should be taken into account in the differential diagnosis
when a woman presents with severe back pain during or after pregnancy. In our current
study, we reviewed the novel literatures that demonstrate the current understanding of and treatment
for PLO. In addition, we retrospectively studied four patients who suffered from back pain
and VCFs during or after pregnancy. We also examine their clinical medicine treatment methods
and outcomes in order to provide evidence for a better understanding of PLO and its relevant medical
treatment.
