Title:Pharmacological Uses of the Plants Belonging to the Genus Commiphora
Volume: 19
Issue: 2
Author(s): Subbiah Latha*, Palanisamy Selvamani and Thangavelu Prabha
Affiliation:
- Department of Pharmaceutical Technology & Centre for Excellence in Nanobio Translational Research, Anna University, Bharathidasan Institute of Technology Campus, Tiruchirappalli, Tamil Nadu,India
Keywords:
Burseraceae, Commiphora, guggul, guggulsterone, myrrh, pharmacokinetics.
Abstract:
Natural products have a unique place in the healthcare industry. The genus Commiphora
emerged as a potential medicinal source with huge benefits as evidenced through its use in various
traditional and modern systems of medicine. Therefore, we aimed to prepare a concise review on the
pharmacological activities and the indigenous uses of various plant species belonging to the genus
Commiphora along with the structural information of various active botanical ingredients present in
these plants based on the published literatures and scientific reports.
To collect the published literatures on Commiphora in various journals; to study and classify the
available information on the pharmacological uses and chemical constituents; and to present the
gathered information as a precise review to serve as a potential reference for future research.
Pharmacological and phytochemical data on Commiphora plant species were collected from various
journals, books, reference materials, websites including scientific databases, etc. for compilation.
This review article describes the various pharmacological properties of plants of Commiphora species
viz., anti-arthritic and anti-inflammatory, anti-atherogenic, antibacterial, anti-coagulant, antidicrocoeliasis,
anti-epileptic, anti-fascioliasis, anti-fungal, anti-heterophyidiasis, anti-hypercholesterolemic,
anti-hyperlipidemic, anti-hypothyroidism, anti-obesity, anti-osteoarthritic, antiosteoclastogenesis,
anti-oxidant, anti-parasitic, anti-pyretic, anti-schistosomiasis, anti-septic, antithrombotic,
anti-ulcer, cardioprotective, COX enzyme inhibitory, cytotoxic /anti-carcinogenic/anticancer,
DNA cleavage, hypotensive, inhibits lipid peroxidation, inhibits NO and NO synthase production,
insecticidal, local anesthetic, molluscicidal, smooth muscle relaxant, and tick repellent activities
along with toxicity studies. Furthermore, the review also included various secondary metabolites
isolated from various species of Commiphora genus along with their chemical structures serving as a
ready resource for researchers.
We conclude that the plant species belonging to the genus Commiphora possesses abundant pharmacological
properties with a huge treasure of diverse secondary metabolites within themselves. This
review indicates the necessity of further in-depth research, pre-clinical, and clinical studies with
Commiphora genus, which may help to detect the unidentified potential of the Commiphora plant
species.
