Title:Antiplatelet Therapy And Percutaneous Coronary Interventions
Volume: 17
Issue: 3
Author(s): René Hameau Davanzo, Alberto Fuensalida Alarcon, Jorge Quitral Calquin, Pablo Sepulveda Varela, Alejandro Martinez Sepulveda, Ramón Corbalán Herreros, Sanjay Patel and Gonzalo Martinez Rodriguez*
Affiliation:
- Division of Cardiovascular Diseases, Pontificia Universidad Católica de Chile, Santiago,Chile
Keywords:
Antiplatelet therapy, percutaneous coronary interventions, thrombosis, angioplasty, clopidogrel, prasugrel, ticagrelor.
Abstract: Dual antiplatelet therapy is one of the cornerstones of modern percutaneous coronary interventions.
The development of new therapeutic agents has significantly reduced ischemic events
at the risk of increased bleeding complications. Therefore, efforts are currently focused on optimizing
therapeutic algorithms to obtain the greatest anti-thrombotic benefit associated with the lowest
risk of bleeding, that is, the greater net clinical benefit.
A significant number of trials evaluating different drug combinations or adjustments in treatment
duration have been completed. However, clinical translation of these results is often difficult due to
the heterogeneity of the therapeutic approaches.
The aim of this manuscript is to provide an updated review of the literature regarding the use of
dual antiplatelet therapy in patients undergoing coronary angioplasty and stenting.
