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General Review Article

咪唑的多功能部分目前和未来的展望

卷 21, 期 11, 2020

页: [1130 - 1155] 页: 26

弟呕挨: 10.2174/1389450121666200530203247

价格: $65

Open Access Journals Promotions 2
摘要

含咪唑化合物自古以来就是一个被广泛研究的领域。随后，它构成了新药开发的重要部分。各种含有咪唑部分的化合物已被合成、评估和上市，用于治疗各种疾病，如抗真菌、抗癫痫、ACE抑制剂等，如图所示。寻找具有更强生物选择性和低副作用的咪唑化合物仍然是药物化学研究的一个活跃领域。这篇综述是为了突出已上市的咪唑环类药物。这篇文章也展示了未来市场上的咪唑类药物作为抗真菌药物的前景，这些药物具有靶向14种促生长因子-去甲基化酶的潜在活性。

关键词: 唑杂环，咪唑，上市咪唑类药物，细胞色素P450

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图形摘要

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