Title:Prediabetic Dysglycemia: Call for Action
Volume: 17
Issue: 1
Author(s): Åke Sjöholm*
Affiliation:
- Department of Internal Medicine, Division of Endocrinology and Diabetology, Gavle Hospital, SE-80324 Gavle,Sweden
Keywords:
Prediabetic dysglycemia, insulin, impaired glucose tolerance, normoglycemia, dysmetabolic syndrome, cardiovascular
risk
Abstract: Different dysglycemic states precede overt type 2 diabetes. Prediabetic dysglycemia also carries
an increased cardiovascular risk per se. Prediabetic dysglycemia may be divided into impaired fasting
glycemia, impaired glucose tolerance and intermediate hyperglycemia. Mixed forms of these are
very common. Dysglycemia develops insidiously for many years and usually produces no symptoms
until very late. It is possible to prevent prediabetic dysglycemia from progressing to manifest type 2
diabetes and it can also be made to return to normoglycemia. The importance of lifestyle interventions,
pharmacological treatment, surgical treatment and community efforts are discussed.