Title:Immunoliposomes: Synthesis, Structure, and their Potential as Drug Delivery Carriers
Volume: 16
Issue: 4
Author(s): Divya Sandeep, Nour M. AlSawaftah and Ghaleb A. Husseini*
Affiliation:
- Department of Chemical Engineering, American University of Sharjah, Sharjah,United Arab Emirates
Keywords:
Cancer, targeted drug delivery, antibodies, antibody fragments, immunoliposomes, receptor upregulation.
Abstract: Immunoliposomes have emerged as attractive drug targeting vehicles for cancer treatment.
This review presents the recent advances in the design of immunoliposomes encapsulating a
variety of chemotherapeutic agents. We provided an overview of different routes that can be used
to conjugate antibodies to the surfaces of liposomes, as well as several examples of stimuliresponsive
immunoliposome systems and their therapeutic potential for cancer treatment.