Title: Lessons from HIV Movement of Macromolecules Inside the Cell
Volume: 1
Issue: 1
Author(s): Oliver T. Fackler, B. Matija Peterlin and Karsten Weis
Affiliation:
Keywords:
HIV, Macromolecules, Response TAR RNA, Trans Activation, RNA polymerase II, TATA-box Binding, Transcription TBP-Associated Factor, TFIIA, Negative Elongation factor, Major histocompatibility
Abstract: Molecular biological investigations of HIV have made fundamental contributions to our understanding of eukaryotic biology. These studies elucidated new paradigms in transcription, RNA and protein export from the nucleus to the cytoplasm, cellular activation, morphology and vesicular trafficking.