Review Article

多囊卵巢综合征的表观遗传标记

卷 27, 期 39, 2020

页: [6727 - 6743] 页: 17

弟呕挨: 10.2174/0929867326666191003154548

价格: $65

摘要

多囊卵巢综合症(PCOS)是一种常见的内分泌和代谢疾病,会影响育龄妇女。 最近的研究表明,基因在PCOS的病因中具有重要作用。 但是,人们对这些基因转录和转录后调控的确切方式知之甚少。 本审查的目的是提供有关miRNA和DNA甲基化作为PCOS的表观遗传标记的最新信息。 此处提供的数据可以得出结论,在选择特定PCOS表型的治疗方法时,可以将microRNA和DNA甲基化视为可能有用的生物标记,因此代表了诊断和治疗PCOS患者的两个重要工具。

关键词: 多囊卵巢综合征,表观遗传标记,miRNA,DNA甲基化,PCOS表型,PCOS治疗。

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