Ischemic cardiomyopathy is considered as the main cause of heart failure in industrialized countries. The condition can occur at any age, but its prevalence increases with age. In general, careful evaluation of the patient's history and physical examination can provide useful information about the underlying causes. Several biomarkers and laboratory variables are very important parameters for physicians during the clinical decision making. Echocardiography along with other imaging and heart failure management techniques can provide key information to clinicians about these parameters. This information can be used to provide adequate medical interventions and improve patient health while reducing the risk of sudden death due to cardiac arrest. This volume of Frontiers in Heart Failure brings forth information about several topics related to assessing the risk of heart failure and treating patients who may be at high risk. Chapters in this volume cover topics such as ischemia, echocardiography, pharmacotherapy, interventional techniques and device therapies. Novel therapies, such as gene and cell strategies are also covered in this volume.

This volume of Frontiers in Heart Failure comprehensively covers the gap between clinical management of heart failure and advanced molecular imaging techniques (SPECT, PET, MRI etc.). These techniques provide valuable evidence to cardiologists for the evaluation and follow-up of heart failure patients. It brings forth established research data regarding the pathophysiology, clinical presentations and therapy of heart failure, in a balance between clinical items and molecular imaging modalities. Readers will also find additional chapters on hybrid cardiovascular imaging techniques as well as guidelines on imaging artifacts and radiation protection. This volume is a useful resource for radiologists, cardiologists, cardiac care nurses and medical physicists.

Pediatric patients require special attention for treating their cardiac conditions and preventing heart failure. Treatment for heart failure in children may involve professionals from multiple medical disciplines. <P></P> Heart Failure in Pediatric Patients describes the pathophysiology, classification and clinical presentation of heart failure in pediatric populations with an emphasis on infants with congenital heart disease. <P></P> Readers will learn about different modes of clinical investigations for pediatric heart patients as well as heart failure in conditions of hypertrophic cardiomyopathy. The book also presents chapters on the management of heart failure including surgery in critical conditions. <P></P> This book explains concepts with interesting images and videos that illustrate and accurately describe cases. it answers the needs of cardiology learners at different levels; undergraduate, postgraduate, specialists and allied professionals who will be able to benefit from the perspective of several cardiologists working at different regional medical centers.

Coronavirus disease 2019 (COVID-19) has affected millions of people across the world. Clinicians and scientists across the globe need all the information of this pandemic on one platform. Today, it is also necessary to find out the association of COVID-19 with various medical comorbidities, and its effect on vulnerable populations that require special medical attention. This information will be helpful for the management of COVID-19. COVID-19: Effects in Comorbidities and Special Populations is a concise and visual reference for information about this viral disease and its relationship with different medical conditions. The book provides comprehensive knowledge covering COVID-19 comorbidities (for example, CVD, Diabetes, lung diseases, etc.), and the incidence in specific groups (for example, children and the elderly). Chapters outline the features and the management of the disease in specific conditions. Key Features: - 12 chapters covering several aspects of COVID-19 management, making this a perfect text book for virologist and medical students - Focused and structured description of different effects of COVID-19 in specific patient groups - Multiple tables and figures which summarizes and highlight important points - Multiple choice questions for learners - Detailed list of references, abbreviations and symbols This book is an essential reference for practicing and training virologists, pulmonologists, medical students and scientists working in research labs, pharmaceutical and biotechnology industries in connection with the control of COVID-19 infection.

This reference summarizes recent advancements in knowledge about cardiovascular disease and pharmacology. The goal of the book is to inform readers about recent findings on cardiovascular therapeutics and how to conduct experiments to evaluate natural products. It presents 10 chapters that cover basic clinical research on cardiovascular diseases and therapeutic agents derived from natural sources. The book concludes with a series of experiments that demonstrate the methods to test the ameliorative effects of 3 phytochemicals: Biochanin A (red clover), Zingiberene (ginger oil) and Betaine (sugar beet). Key Features - 10 chapters that highlight recent research cardiovascular medicine and pharmacology - Covers knowledge about basic cardiovascular physiology, congestive heart failure treatment and the treatment of heart inflammation. - Covers uses, benefits, and drawbacks of numerous rodent and non-rodent animal models for studying CVD - Updates readers about 21st-century CRISPR-cas9 technology and its uses in CVD. - Covers the significance of Indian Ayurvedic techniques on the cardiovascular system, - Covers information about nutraceuticals for CVD therapy - Includes experiments to evaluate 3 phytochemicals for the treatment of different heart diseases such as hypertension, obesity-cardiomyopathy and the mitigation of inflammatory cytokines in myocardial infarction. This book is an informative resource for cardiologists, and researchers working in the field of cardiovascular pharmacology. It also helps readers to understand the benefits of herbal medications that are commonly available for consumption in homes.

This book provides a quick update on key aspects of current anesthesia practice. Book chapters are written in a concise manner to enable readers (anesthesia providers and medical students) to quickly refresh their knowledge, and understand the essential points about key topics. The chapters are written by eminent clinicians who are also outstanding teachers in their respective anesthesia training programs. Topics covered in this volume include: trauma, trauma anesthesia, regional anesthesia, upper extremity blocks, lower extremity blocks, ultrasound, the use of ultrasound for blocks and vascular access, coagulation, hemostasis, transfusion, anticoagulants and their reversal, issues in pediatric anesthesia, and pediatric trauma, as well as obstetrical anesthesia. The book serves as a handbook for advanced anesthesia professionals and a textbook for medical students.

This book provides an updated information about major systems for anesthesia in patients with concomitant diseases. Book chapters are designed to allow anesthesia providers to refresh their knowledge, and be able to focus on the current issues in these subspecialty areas. Readers will be able to approach anesthesia cases more effectively with the information provided. The chapters are written by eminent clinicians who are also outstanding teachers in their respective anesthesia training programs. Topics covered in this volume include: thoracic anesthesia, cardiac anesthesia, anesthesia in the ENT patient, neuroanesthesia, intensive care / ICU medicine, medical ethics, and interesting cases. The book serves as a handbook for advanced anesthesia professionals and a textbook for medical students.

In recent years, there have been many advances in the safe management of the patient's airway, a cornerstone of anesthetic practice. An Update on Airway Management brings forth information about new approaches in airway management in many clinical settings. &lt;p&gt;&lt;/p&gt; This volume analyzes and explains new preoperative diagnostic methods, algorithms, intubation devices, extubation procedures, novelties in postoperative management in resuscitation and intensive care units, while providing a simple, accessible and applicable reading experience that helps medical practitioners in daily practice. The comprehensive updates presented in this volume make this a useful reference for anesthesiologists, surgeons and EMTs at all levels. &lt;p&gt;&lt;/p&gt; Key topics reviewed in this reference include: &lt;p&gt;&lt;/p&gt; &middot; New airway devices, clinical management techniques, pharmacology updates (ASA guidelines, DAS algorithms, Vortex approach, etc.), &lt;p&gt;&lt;/p&gt; &middot; Induced and awake approaches in different settings &lt;p&gt;&lt;/p&gt; &middot; Updates on diagnostic accuracy of perioperative radiology and ultrasonography &lt;p&gt;&lt;/p&gt; &middot; Airway management in different settings (nonoperating room locations and emergency rooms) &lt;p&gt;&lt;/p&gt; &middot; Airway management in specific patient groups (for example, patients suffering from morbid obesity, obstetric patients and critical patients) &lt;p&gt;&lt;/p&gt; &middot; Algorithms and traditional surgical techniques that include emergency cricothyrotomy and tracheostomy in &lsquo;Cannot Intubate, Cannot Ventilate&rsquo; scenarios. &lt;p&gt;&lt;/p&gt; &middot; Learning techniques to manage airways correctly, focusing on the combination of knowledge, technical abilities, decision making, communication skills and leadership &lt;p&gt;&lt;/p&gt; &middot; Special topics such as difficult airway management registry, organization, documentation, dissemination of critical information, big data and databases

In recent years, we have witnessed significant advances in obstetric anesthesia, providing greater safety for the mother and the fetus, as well as an improvement in pain management procedures during labor. This volume presents updates in obstetrics and gynecology that are reflective of the changes in the demographics and associated clinical presentations of gynecological pathologies. It compiles state of the art information on the subject in 20 chapters contributed by more than 50 experts in obstetric anesthesia. The main objective of this volume is to inform and update readers about the different aspects essential to the practice of anesthesia and analgesia during pregnancy, labor, cesarean section and puerperium. The contents also include information about the management of pregnant women with different pathologies and high-risk pregnancies. The authors believe that it is essential for all anesthesiologists to be aware of the latest advances and well-contrasted scientific evidence that will allow them to carry out their usual clinical activity. The volume approaches the subject in a clear and didactic way for the benefit of all professionals involved in this field, including anesthesiologists, gynecologists, obstetricians, surgeons, clinicians and allied healthcare service providers.

Triple negative breast cancers (TNBC) are a biologically aggressive form of breast cancer and constitute approximately 10-15% of all breast cancer patients. Distant metastasis, lack of clinically targeted therapies and prognostic markers, makes the disease difficult to treat. Till now not much work has been carried out on this deadly disease. This book provides an overview of TNBC etiology, its treatment strategies and prognostic markers to identify the outcome of standard therapies. Signalling pathways namely cell proliferation, angiogenesis, invasion and metastasis, apoptosis, autophagy and others involved in complicating the disease have been described in the chapters to convey an understanding about the disease mechanisms. All the possible drugs either in pre-clinical or clinical stages have also been mentioned with data that depicts their efficiency in targeting altered genes. The book also introduces the reader to herbal medicine exhibiting high potency to target TNBC, their synthetic analogs used during chemotherapy and their ability to fight against chemoresistance. The concept of phytonanotechnology has also been discussed. The book helps create awareness among a broad range of readers about TNBC. It points to prioritizing the upgradation of health care facilities and re-designing future treatment strategies to provide maximum benefit to breast cancer patients.