Eukaryotic cells contain specific structural segments that determine the cellular
biomechanical characteristics, with the aid of numerous molecular structures. Cell
mechanics is mostly determined by the cytoskeleton dynamics in coordination with the
extra- and intra-cellular milieu. Cells can sense mechanical forces and, by signalling
system, convert them to biological response through mechanotransduction pathways. Cells
of mesenchymal origin are specially sensitive and responsive to mechanical forces because
they are involved in building of the biomechanically efficient tissues for force propagation.
Keywords: Actin, adhesion molecules, cell migration, fluid shear, intermediate
filaments, microtubules.
