This chapter evaluates disorders of regulatory mechanisms such as achalasia
and Hirschsprung Disease and disorders of effector mechanisms such as reflux disease,
systemic sclerosis of the GI tract and Colonic Diverticular Disease. Definitions,
pathogenesis, course, treatment and complications are revealed as well as the
bioengineering thoughts of the authors are elucidated.
Keywords: Achalasia, biomechanics, diverticular disease, gastroesophageal
reflux disease, Hirschsprung Disease, motility.