Sepsis-induced myocardial dysfunction (SIMD) is a common and reversible
complication in severe sepsis and septic shock patients. Its pathogenesis is complex and
probably mediated by cytokines. Echocardiography is the gold standard to make the
diagnosis of SIMD. Cardiac biomarkers have a high negative predictive value for
SIMD. Norepinephrine is the first line vasopressor. Inotropic drugs should be used in
the case of left ventricular systolic dysfunction associated with persisting tissular
hypoperfusion.
Keywords: Diastolic dysfunction, Echocardiography, Heart failure, Hemodynamic,
Monitoring, Mortality, Natriuretic peptides, Sepsis, Septic cardiomyopathy, Septic shock,
Severe sepsis, Troponins.
