Association of metabolic abnormalities including glucose intolerance,
hypertension, central obesity and dyslipidemia comprise what is called “Metabolic
Syndrome (MS)”. It is known that MS is a risk factor for both diabetes and
cardiovascular disease (CVD). Non-alcoholic fatty liver disease (NAFLD) has also
emerged as an important metabolic disease which is associated with both diabetes and
cardiovascular disease. South Asian countries and particularly India have very high
prevalence rates of MS and NAFLD. Moreover, the prevalence of type 2 diabetes and
premature coronary artery disease is very high. However, the link between MS, NAFLD
and CVD are not very well defined. This chapter reviews in detail the association of MS
with CVD and also NAFLD and CVD. It also discusses the controversies with MS and
highlights current strategies involved in management of MS and NAFLD.
Keywords: Activity, behavior, cardiovascular disease, cardiovascular risk, global
health, hepatology, intervention, lifestyle, liver disease, metabolic syndrome,
obesity, overweight, south Asians, type 2 diabetes, wellness.
