Cancer is a disease which brings about a huge sense of terror. It has therefore,
been a threat to human beings globally. Many organic and metallo chemotherapeutics are
currently available in the market for the treatment of different sorts of cancers, but, still
there is no drug which can curb this disease at late stages completely and worse, most drugs
exhibit severe side effects. The choice for cancer treatment seems to be nanodrugs, which
are effective at much lower concentrations and with much less side effects. Nanodrugs are
the magic bullets, designed to be selective for tumor tissue and to act only on cancer cells.
Nanodrugs are macromolecules or nanoparticles that function as targeted carrier systems to
deliver active anticancer drug exclusively at the site of cancer. The well known anticancer
chemotherapeutics cisplatin, carboplatin, 5-fluorouracil, bleomycin, paclitaxel,
doxorubicin, vinblastin and topotecan etc., but also novel drugs including nucleic acids and
proteins can be incorporated into these delivery systems. Drugs become active only at the
site of cancer cells. A consideration of the unique properties of nanodrugs seems to bring
about a revolution in cancer treatment which is the urgent need of time. The present chapter
describes the huge diversity of nanodrugs and highlights the few principles of their
mechanisms. Moreover, the superiority of nano anticancer modalities in comparison to the
conventional chemotherapeutic anticancer drugs will be discussed. Recent patents in the
field have been discussed under different sections of the chapter. Recent rocketing
developments in the field will be introduced and emphasis has been laid on future
perspectives.
Keywords: Cancer epidemiology, chemotherapeutics, chemotherapy, conventional
anticancer drugs, dendrimers nanodrugs, drug delivery, future perspectives,
inorganic material containing nanodrugs, liposomal nanodrugs, magic bullets,
mechanism of action of nanodrugs, micellar nanodrugs, nanodrug diversity,
nanodrugs, nanotechnology, organic material based nanodrugs, polymeric
nanodrugs, recent developments, scope of nanodrugs, targeted medical tools.
