A new emerging field that combines nanoscale materials and biosensor technology is
receiving increased attention. Nanostructures have been used to achieve direct wiring of enzymes to
electrode surfaces, to promote electrochemical reactions, impose nano barcodes on biomaterials, and
amplify the signal from biorecognition events. NP-based sensors have found wide spread applications
in the environmental and medical applications for their sensitivity, specificity, rapidity, simplicity, and
cost-effectiveness.
The aim of this chapter, without pretending to being exhaustive, is mainly to review recent important
achievements about metal nanoparticles preparation, their bio modification and the new applications for
protein detections by means of a set of selected recent publications.
Keywords: Biosensors; metal nanoparticles; biomodification; protein detections.
