We present herein the latest three-dimensional (3D)/four-dimensional (4D) sonographic studies on fetal
heart and blood vessels using STIC (spatiotemporal image correlation) or real-time 3D fetal echocardiography.
These new 3D/4D ultrasound techniques include VOCAL (Virtual Organ Computer-aided AnaLysis), TUI
(Tomographic Ultrasound Imaging), SonoVCAD (Sonography Based Volume Computer Aided Diagnosis),
color/power Doppler ultrasound and HD (High-Definition)-flow, B-flow and inversion mode. Fetal 3D/4D
echocardiography provides a novel means for evaluation of fetal heart and blood vessels in 3D in real time, and of
fetal intracardiac hemodynamics in the second and third trimesters. These novel techniques may assist in the
evaluation of fetal cardiac anatomy and hemodynamics, and offer the potential advantages relative to conventional
two-dimensional fetal echocardiography and Doppler flow mapping. 3D/4D ultrasound may be an important
modality in future fetal cardiac research and in evaluation of congenital heart disease in the fetus.
