Aberrant recognition of receptivity events in the vascular endothelial growth factor cascade
involves an excessive response in terms of vascular endothelial cell proliferation beyond the simple
dynamics of a purely angiogeneic adaptive response. The implicit development of malignancy as a
term of reference with regard to the pathogenesis of malignancy is a further documented or registered
imprint towards the evolution of systems to spread based on such angiogenesis.
Keywords: angiogenesis, template, adaptive response.