This book chapter explores the multifaceted role of polymers in the field of
controlled drug delivery, providing a comprehensive overview of the latest
advancements and applications. Polymers have emerged as pivotal components in
designing drug delivery systems due to their tunable properties, biocompatibility, and
ability to modulate drug release kinetics. The chapter delves into the various types of
polymers employed in controlled drug delivery, including natural, synthetic, and hybrid
polymers, highlighting their unique characteristics and functionalities. The discussion
encompasses the design principles behind polymer-based drug delivery systems,
elucidating how factors such as molecular weight, architecture, and composition
influence drug release profiles. Additionally, the chapter scrutinizes the diverse
strategies employed to achieve controlled drug delivery, such as micelles,
nanoparticles, and hydrogels, each offering tailored solutions for specific therapeutic
needs. Special emphasis is placed on the biodegradability and biocompatibility of
polymers, ensuring safety and efficacy in clinical applications. Through a critical
examination of recent research and case studies, this chapter provides valuable insights
for researchers, practitioners, and students in the pharmaceutical and biomaterials
fields. It serves as a comprehensive resource for understanding the pivotal role of
polymers in advancing controlled drug delivery technologies, ultimately contributing to
the evolution of more efficient and patient-friendly therapeutic interventions.
Keywords: Biodegradable polymers, Controlled release, Drug delivery systems, Encapsulation, Hydrogels, Micelles, Nanoparticles, Oral delivery, Polymersomes, Stimuli-responsive polymers, Sustained release, Targeted drug delivery, Transdermal delivery, Vesicles, Water-soluble polymers.
