One of the key reasons for death is blood loss or hemorrhage from trauma or
surgeries. Management of bleeding by utilizing suitable hemostatic agents is therefore
important to diminish related complications and mortality. In recent years, the
application of bioactive glasses for hemostasis has shown promising results in both in
vitro and in vivo. In this chapter, we will highlight the mechanism of action of bioactive
glasses in accelerating hemostasis, review various forms of bioactive glasses and their
composites that have been assessed for potential application in promoting hemostasis
and stopping bleeding, and briefly include future perspectives.
Keywords: Activated partial thromboplastin time, Bioactive glasses, Bioactive glasses particles, Bioactive glass microspheres, Bioactive glasses/polymer composites, Biomaterials, Biomedical application, Bleeding, Blood coagulation, Fibers, Hydrogels, Hemorrhage, Hemostasis, Hemostatic application, Mesoporous bioactive glasses, Platelet adhesion, Prothrombin time, Sponges, Thrombin, Thrombus formation.
