Nutraceuticals have gotten a lot of attention in recent years because of the
health-promoting and disease-prevention properties along with their nutritional value.
The increasing quantity of widely viable nutraceuticals and their wide range of uses
indicate the domination of these products around the world. Nutraceuticals contain a
variety of health advantages and functions; however, most nutraceuticals degrade
quickly in the gastrointestinal tract and have low bioavailability. Different innovative
drug delivery-containing carrier technologies are continually being researched in order
to improve the efficacy and bioavailability of herbal medications. To overcome hurdles
and enable efficient application, a unique carrier system is becoming increasingly
important. This chapter provides an insight into nanoencapsulated nutraceuticals'
physical and gastrointestinal stability, as well as their bioavailability, which are all
taken into account. The existing limitations, synthesis, and applications of different
lipid-based nanocarriers (including niosomes and liposomes) and lipid nanoparticles
(SLNs and NLCs) are examined critically. This study also attempts to document the
most recent advancements and problems in the field of nanonutraceuticals, a cuttingedge subject that uses nanotechnology to encapsulate bioactive substances in order to
enhance their medicinal effectiveness and release profile.
Keywords: Bioavailability, Lipid nanoparticles, Nanocarriers, Nanonutraceuticals.