Quinoline is one of the significant moieties in the construction of new
pharmaceuticals since it is a notable scaffold among heterocyclic compounds. The
derivatives of quinoline which are biologically active compounds, are acknowledged as
prominent scaffolds in drug discovery. Quinoline-based heterocycle scaffolds have
recently become very important in medicinal chemistry because of their important
pharmacological and biological properties. These substances' importance in the finding
and formation of pioneering medicines for the treatment of various diseases is an
example of their value. Using literature that has been published in the last five years,
the current study describes the synthesis of different quinoline-based heterocycle
scaffolds and their advantageous medicinal uses, especially as anti-inflammatory
agents.
Keywords: Anti-inflammatory agents, Azoimine, Biological properties, Heterocyclic compounds, Isoxazole, Ibuprofen, Medicinal chemistry, Molecular docking, Oxadiazole, Pyran, Pyrazolo quinoline, Pharmacological properties, Quinoline derivatives, Quinazolinones, Sulfonamides, Thiazolidinone, Triazine and triazole.
