In current days, imidazoles and benzimidazoles are vital classes of Nheterocyclic compounds. One of the 5-membered heterocyclic compounds is imidazole
ring structure through 3 carbon and 2 nitrogen atoms and in imidazole structure, N is
occupied in 1st and 3rd location in five-membered ring system. It is planer in structure.
The imidazole moiety is an essential of numerous significant natural products, together
with histamine, purine, histidine and nucleic acid. On the other hand, benzimidazole
covers six-membered benzene ring system fused with five-member imidazole ring
systems. Benzimidazole core unit molecules continue to be the indispensable focus
among the available heterocyclic compounds because of more than a few
pharmacological and biological properties. Benzimidazoles achieve the center of
attention due to their stability, outstanding bioavailability, and wide range of biological
competence. The current study discloses and discusses the biological activities of
imidazole and benzimidazole scaffolds widely used as anti-inflammatory agents.
Keywords: Anti-inflammatory, Benzimidazoles, Biological activity, Imidazoles medicinal chemistry.
