Low molecular weight hydrogelators (LMOHGs) are extremely promising
synthons, in the bottom-up fabrication of supramolecular soft materials. In recent years,
significant contributions to Peptide-based hydrogels coined as Bioinspired fragments
have been made. In this book chapter, our effort lies to module two different aspects:
Firstly the underlying guidelines and principles for the tailoring of scaffolds that would
lead to hydrogel formation and an overview of the role of non-covalent
interactions/chemical functionalization that are the key components of various selfassembly processes. In the second section, we aim to bring together our recent
achievements with designer assembly with respect to their self-aggregation behavior
and applications mainly in the biomedical arena like drug delivery carrier design,
antimicrobial, anti-inflammatory as well as wound healing properties. We anticipate
that this article would provide a conceptual demonstration of the different approaches
taken toward the construction of these task-specific designer hydrogels.
Keywords: Anti-inflammatory, Antimicrobial activity, Biocompatibility, Drug delivery carrier, Mechanical strength, Proteolytic stability, Wound healing.
