Cell adhesion is a complex mechanism that involves a dynamic interaction
between the cell surface protein and specific ligands. It has become a crucial part to be
understood when it comes to cell adhesion to biomaterial, especially in the tissue
engineering field. In this chapter, we narratively discussed the basic principle of cell
adhesion and the factors that affect this process. The characterisation of cells on
biomaterials has also been discussed, as well as their application in the tissue
engineering context.
Keywords: Biomaterial, Cell adhesion, Cell signaling, Microenvironment, Tissue engineering.