The medicinal plants are widely used to treat diverse ailments and diseases,
including gastro-intestinal symptoms, cardiovascular diseases, skin disorders,
respiratory and infectious diseases, accelerating in recent years. Plants are rich in a
wide variety of secondary metabolites, such as alkaloids, tannins, flavonoids, and
phenolic compounds, found in vitro to have antimicrobial properties and could assist in
the discovery of novel drugs. The search for novel antimicrobial compounds, especially
against multidrug-resistant pathogens from aromatic and herbal plants, is an essential
line of scientific research. This review attempts to summarize the in vivo studies of the
antimicrobial activity of medicinal plants and their biologically active compounds. The
chemical composition of biologically active compounds with antimicrobial is also
addressed.
Keywords: Antimicrobials, Herbal plants, Secondary metabolites.