Kidney-related
biomarkers can provide structural and functional information about different
parts of the nephron. These biomarkers can be used to evaluate glomerular,
tubular, or interstitial injury, inflammation, or repair, and glomerular or tubular
function. Furthermore, biomarkers can improve the acute kidney injury diagnosis
in various clinical conditions, including acute interstitial nephritis, acute tubular
injury, hepatorenal and cardiorenal syndrome, ischemic and nephrotoxic acute kidney
injury, and drug-induced acute kidney injury. Biomarkers might be used as an additional
precision medicine tool in managing patients with acute kidney injury; they can
help with clinical decision-making and impact patient outcomes. In this
chapter, we reviewed the utility of biomarkers used in acute kidney injury.
Keywords: Acute kidney injury, Biomarkers, Nephrotoxicity, Tubular injury.
