Parkinson
disease is a progressive neurodegenerative disorder that affects motor control
of the body. The disorder is associated with the loss of neurons due to formation
of protein aggregates that leads to the development of apoptosis and degeneration
of the neurons. The disease progresses slowly, making it difficult to identify
it at early stage. But the availability of potential therapeutic biomarkers in analysis
and early identification of PD is of great importance. The current review discusses
here the molecular biology, pathophysiology and availability of potential biomarkers
associated with the PD condition.
Keywords: Parkinson disease, Alpha synuclein, neurodegenerative disorders, motor control, Dopamine.
