Point-of-care (POC) diagnostic analysis is a fast rising arena that goals to
improve the rapidness, low-cost, sensitive and selective in-vitro diagnostic analysis
platforms that are independent, moveable, and can be used everywhere from current
clinics to isolated and low resource regions. In addition, surface enhanced Raman
spectroscopy (SERS) offers a suitable sensory stage whereby objective particles at
smaller concentration are recognized, potentially identifying a particular substances.
There are some analytical methods which can induce motivated Raman scattering,
significantly attractive the possibility of Raman scattering, but most of these
procedures need ultra-fast tunable lasers and microscopy set-ups making them
impossible for most users. SERS exploits surface plasmons to improve Raman
scattering by numerous orders of magnitude, without lacking various equipment than
traditional Raman spectroscopy. As a result, SERS has been extensively useful in a
selection of research activities using various substrates, one of which is a smartphone
based biosensors. In outlining the development of SERS methods over the past few
years joined with new expansions in smartphone based biosensors, metal and metal
oxide nanomaterials, low-cost paper diagnostics, and high-quantity of microfluidics, a
wide-ranging number of novel potentials display the possible for decoding SERS
biosensors to the POC.
Keywords: Lateral Flow-assay, Point-of-care Application, Smartphone, Surface Enhanced Raman Spectroscopy.
