We all recognize the typical signs and symptoms of COVID-19 (fever,
shortness of breath, persistent non-productive cough). Less common symptoms are
headaches, confusion (talking nonsense), numbness/hypoesthesia, seizure
(convulsions), vomiting, loss of smell (anosmia), and sense of taste (ageusia). It can be
noted that this group of symptoms consisted mostly of neurological complaints.
COVID-19 causes CNS damage with various mechanisms. For example, anosmia or
hyposmia is seen quite frequently among individuals even with mild COVID-19.
Therefore, physicians should be alert in noting nervous system-related symptoms and
findings that can be seen in the course of COVID-19.
Keywords: ACE2 receptors, Ageusia, Anosmia, Confusion, Cognitive disorders,
COVID-19, Headache, Neurology, Pandemic.
