The importance of understanding the pathogenesis of infectious agents is in
the diagnosis of the diseases and finding new treatments. In the case of P. aeruginosa
pathogenesis, the issue is extremely broad and complex. Also, many aspects of its
pathogenesis remain unknown to researchers. At a glance, P. aeruginosa causes acute
and chronic infections. In addition, P. aeruginosa is an opportunistic bacterium that is
highly dangerous in immunocompromised patients. In some cases, it can also threaten
human life and causes the death of the patients. The ability of P. aeruginosa to cross
the body barriers is so fascinating, which can penetrate the skin and even depths of the
bone and joints. Although the pathogenesis of P. aeruginosa depends on many factors,
it is attributed to several diseases including, bacteremia, keratitis, pneumonia, bone and
joints infection, respiratory tract infection, urinary tract infection, skin and soft tissue
infection, ear infection, endocarditis, central nervous system infection, enteric
infection, mastitis and, etc. The wide range of diseases caused by P. aeruginosa clearly
demonstrated the importance of this bacterium in the fields of medicine.
Keywords: Acute and chronic infection, Cystic fibrosis, Endocarditis,
Opportunistic pathogen, Pathogenicity, Pneumonia, Urinary tract infection.
