Bone Marrow (BM) is a major hematopoietic organ in the human body
being the main primary lymphoid organ; it is the source of production of all blood
lineages. These cells are produced through an interaction between BM hematopoietic
cells and the surrounding microenvironment in a unit called the stem cell niche that
involves several cytokines, growth factors and transcriptional factors. The following
chapter will entail an overview of MSCs, their isolation and clinical application.
Keywords: Basic Science, Bone Marrow Aspirate, Bone Marrow Aspirate
Concentrate (BMAC), Expanded stem cells, MSCs, Stem cell differentiation.
